Prof. Dr. Günter K. Stalla: Selected papers since 2010


Albani A, Perez-Rivas LG, Dimopoulou C, Zopp S, Colon-Bolea P, Roeber S, Honegger J, Flitsch J, Rachinger W, Buchfelder M, Stalla GK, Herms J, Reincke M, Theodoropoulou M. The USP8 mutational status may predict long-term remission in patients with Cushing’s disease. Clin Endocrinol 2018; Epub ahead of print

Auer MK, Fuss J, Nieder TO, Briken P, Biedermann SV, Stalla GK, Beckmann MW, Hildebrandt T. Desire to have children among transgender people in Germany: a cross-sectional multi-center study. J Sex Med 2018; 15(5):757-67.

Valassi E, Feelders R, Maiter D, Chanson P, Yaneva M, Reincke M, Krsek M, Toth M, Webb SM, Santos A, Paiva I, Komerdus I, Droste M, Tabarin A, Strasburger CJ, Franz H, Trainer PJ, Newell-Price J, Wass JA, Papakokkinou E, Ragnarsson O, ERCUSYN Study Group. Worse health-related quality of life at long-term follow-up in patients with Cushing’s disease than patients with cortisol producing adenoma. Data from the ERCUSYN. Clin Endocrinol 2018; (Epu ahead of print)

Athanasoulia-Kaspar AP, Popp KH, Stalla GK. Neuropsychiatric and metabolic aspects of dopaminergic therapy: perspectives from an endocrinologist and a psychiatrist. Endocr Connect 2018; 7(2):R88-R94.

Auer MK, Ebert T, Pietzner M, Defreyne J, Fuss J, Stalla GK, T’Sjoen G. Effects of sex hormone treatment on the metabolic syndrome in transgender individuals: focus on metabolic cytokines. J Clin Endocrinol Metab 2018; 103(2):790-802.

Perez-Rivas LG, Theodoropoulou M, Puar TH, Fazel J, Stieg MR, Ferrau F, Assie G, Gadelha MR, Deutschbein T, Fragoso MC, Kusters B, Saeger W, Honegger J, Buchfelder M, Korbonits M, Bertherat J, Stalla GK, Hermus A, Beuschlein F, Reincke M. Somatic USP8 mutations are frequent events in corticotroph tumor progression causing Nelson’s tumor. Eur J Endocrinol 2018; 178(1):59-65.

Kann PH, Bergmann S, Bidlingmaier M, Dimopoulou C, Pedersen BT, Stalla GK, Weber MM, Meckes-Färber S. Design oft he growth hormone deficiency and efficacy of treatment (GET) score and non-interventional proof of concept study. BMC Endocr Disord 2018; 18(1):10.

Gebert D, Auer MK, Stieg MR, Freitag MT, Lahne M, Fuss J, Schilbach K, Schopohl J, Stalla GK, Kopczak A. De-masking oxytocin-deficiency in craniopharyngioma and assessing ist link with affective function. Psychoneuroendocrinology 2017; 88:61-9.

Schöfl C, Petroff D, Tönjes A, Grussendorf M, Droste M, Stalla G, Jaursch-Hancke C, Störmann S, Schopohl J. Incidence of myocardial infarction and stroke in acromegaly patients: results from the German Acromegaly Registry. Pituitary 2017; 20(6):635-42.

Dimopoulou C, Stalla GK. Testosterone deficiency and dementia. Dtsch Med Wochenschr 2017; 142(15):1102-5.

Di Dalmazi G, Quinkler M, Deutschbein T, Prehn C, Rayes N, Kroiss M, Berr CM, Stalla GK, Fassnacht M, Adamski J, Reincke M, Beuschlein F. Cortisol-related metabolic alterations assessed by mass spectrometry assay in patients with Cushing’s syndrome. Eur J Endocrinol 2017; 177(2):227-37.

Berr CM, Stieg MR, Deutschbein T, Quinkler M, Schmidmaier R, Osswald A, Reisch N, Ritzel K, Dimopoulou C, Fazel J, Hahner S, Stalla GK, Beuschlein F, Reincke M. Persistence of myopathy in Cushing’s syndrome: evaluation oft he German Cushing’s Registry. Eur J Endocrinol 2017; 176(6):737-46.

Geraedts VJ, Andela CD, Stalla GK, Pereira AM, van Furth WR, Sievers C, Biermasz NR. Predictors of quality of life in acromegaly: no consensus on biochemical parameters. Front Endocrinol (Lausanne) 2017;8:40.

Auer MK, Liedl A, Fuss J, Nieder T, Briken P, Stalla GK, Hildebrandt T, Biedermann SV, Sievers C. High impact of sleeping problems on quality of life in transgender individuals: A cross-sectional multicenter study. PLoS One 2017;12(2):e0171640.

Franck SE, Korevaar T, Petrossians P, Daly AF, Chanson P, Jaffrian-Rea M, Brue T, Stalla GK, Carvalho D, Colao AA, Hana V, Delemer B, Montanana CF, Van der Lely AJ, Beckers A, Neggers SJ. A multivariable prediction model for pegvisomant dosing monotherapy and in combination with long-acting somatostatin analogues. Eur J Endocrinol 2017;176(4):421-30.

Dimopoulou C, Leistner SM, Ising M, Schneider HJ, Schopohl J, Rutz S, Kosilek R, Frohner R, Stalla GK, Sievers C. Body image perception in acromegaly is not associated with objective acromegaly changes, but depends on depressive symptoms. Neuroendocrinology 2017;105(2):115-22.

Ciato D, Mumbach AG, Paez-Pereda M, Stalla GK. Currently used and investigational drugs for Cushing’s disease. Expert Opin Investig Drugs 2016; 26(1):75-84.

Auer MK, Cecil A, Roepke Y, Bultynck C, Pas C, Fuss J, Prehn C, Wang-Sattler R, Adamski J, Stalla GK, T’Sjoen G. 12-months metabolic changes among gender dysphoric individuals under cross-sex hormone treatment: a targeted metabolomics study. Sci Rep 2016;6:37005.

Auer MK, Stalla GK, Stieg MR. Investigating the role of cortisol and growth hormone in fatty liver development: fatty liver index in patients with pituitary adenomas. Pituitary 2016; 19(5):461-71.

Krewer C, Schneider M, Schneider HJ, Kreitschmann-Andermahr I, Buchfelder M, Faust M, Berg C, Wallaschowfski H, Renner C, Uhl E, Koenig E, Jordan M, Stalla GK, Kopczak A. Neuroendocrine disturbances one to five or more years after traumatic brain injury and aneurysmal subarachnoid hemorrhage: data from the German database on hypopituitarism. J Neurotrauma 2016; 33(16):1544-53.

Auer MK, Stieg MR, Hoffmann J, Stalla GK. Is insulin-like-growth-factor-I a good marker for treatment adherence in growth-hormone deficiency in adulthood? Clin Endocrinol (Oxf); 84(6):862-9.

Kopczak A, Krewer C, Schneider M, Kreitschmann-Andermahr I, Schneider HJ, Stalla GK. The development of neuroendocrine disturbances over time – longitudinal findings in patients after traumatic brain injury and subarachnoid hemorrhage. Int J Mol Sci 2015; 17(1). pii E2.

Petroff D, Tönjes A, Grussendorf M, Droste M, Dimopoulou C, Stalla G, Jaursch-Hanke C, Mai M, Schopohl J, Schöfl C. The incidence of cancer amongst acromegaly patients: results from the German Acromegaly Registry. J Clin Endocrinol Metab 2015; 100(10):3894-902.

Sievers C, Baur DM, Schwanke A, Buchfelder M, Droste M, Mann K, Stalla GK. Prediction of therapy response in acromegalic patients under pegvisonmant therapy within the German ACROSTUDY cohort. Pituitary 2015;18(6):916-23.

Perez-Rivas LG, Theodoropoulou M, Ferrau F, Nusser C, Kawaguchi K, Stratakis CA, Faucz FR, Wildemberg LE, Assie G, Beschorner R, Dimopoulou C, Buchfelder M, Popovic V, Berr CM, Toth M, Ardisasmita AI, Honegger J, Bertherat J, Gadelha MR, Beuschlein F, Stalla G, Komada M, Korbonits M, Reincke M. The gene of the ubiquitin-specific protease 8 is frequently mutated in adenomas causing Cushing’s disease. J Clin Endocrinol Metab 2015;100(7):E997-1004.

Dimopoulou C, Geraedts V, Stalla GK, Sievers C. Neuropsychiatric and cardiometabolic comorbidities in patients with previously diagnosed Cushing’s disease: a longitudinal observational study. BMJ Open 2015;5(3):e006134.

Leistner SM, Klotsche J, Dimopoulou C, Athanasoulia AP, Roemmler-Zehrer J, Pieper L, Schopohl J, Wittchen HU, Stalla GK, Fulda S, Sievers C. Reduced sleep quality and depression associate with decreased quality of life in patients with pituitary adenomas. Eur J Endocrinol 2015;172(6):733-43.

Schöfl C, Grussendorf M, Honegger J, Tönjes A, Thyroke-Gronostay D, Mayr B, Schopohl J: participants of the German Acromegaly Register. Failure to achieve disease control in acromegaly: cause analysis by a registry-based survey. Eur J Endocrinol 2015;172(6):351-6.

Riebold M, Kozany C, Freiburger L, Sattler M, Buchfelder M, Hausch F, Stalla GK, Paez-Pereda M. A C-terminal HSP90 inhibitor restores glucocorticoid sensitivity and relieves a mouse allograft model of Cushing’s disease. Nat Med 2015;21(3):276-80.

Petersenn S, Beckers A, Ferone D, Van der Lely AJ, Bollerslev J, Boscaro M, Brue T, Bruzzi P, Casanueva FF, Chanson P, Colao AA, Reincke M, Stalla GK, Tsagarakis S. Therapy of endocrine disease: Outcomes in patients with Cushing’s disease undergoing transsphenoidal surgery: systematic review assessing criteria used to define remission and recurrence. Eur J Endocrinol 2015;172(6):R227-39.

Auer MK, Sack M, Lenz JN, Jacovcevski M, Biedermann SV, Falfan-Melgoza C, Deussing J, Steinle J, Bielohuby M, Bidlingmaier M, Pfister F, Stalla GK, Ende G, Weber-Fahr W, Fuss J, Gass P. Effect of a high-caloric diet and physical exercise on brain metabolite levels: a combined proton MRS and histologic study. J Cereb Blood Flow Metab 2015;35(4):554-64.

Dimopoulou C, Schopohl J, Rachinger W, Buchfelder M, Honegger J, Reincke M, Stalla GK. Long-term remission and recurrence rates after first and second transsphenoidal surgery for cushing's disease: Care reality in the munich metropolitan region. Eur J Endocrinol 2014;170(2):283-92.

Kopczak A, Kilimann I, Von Rosen F, Krewer C, Schneider HJ, Stalla GK, Schneider M. Screening for hypopituitarism in 509 patients with traumatic brain injury or subarachnoid hemorrhage. J Neurotrauma 2014;31(1):99-107.

Dimopoulou C, Athanasoulia AP, Hanisch E, Held S, Sprenger T, Toelle TR, Roemmler-Zehrer J, Schopohl J, Stalla GK, Sievers C. Clinical characteristics of pain in patients with pituitary adenomas. Eur J Endocrinol 2014;171(5):581-91.

Kopczak A, Stalla GK. Neuroendocrine disorders after traumatic brain injury. A review for clinicians. Tägliche Praxis 2014;55(2):281-91.

Roemmler-Zehrer J, Geigenberger V, Störmann S, Losa M, Crippa V, Otto B, Bidlingmaier M, Dimopoulou C, Stalla GK, Schopohl J. Food intake regulating hormones in adult craniopharyngioma patients. Eur J Endocrinol 2014;170(4):627-35.

Droste M, Domberg J, Buchfelder M, Mann K, Schwanke A, Stalla G, Strasburger CJ. Therapy of acromegalic patients exacerbated by concomitant type 2 diabetes requires higher pegvisomant doses to normalise IGF1 levels. Eur J Endocrinol 2014;171(1):59-68.

Stalla GK, Athanasoulia AP, Führer D, Frank-Herrmann P, Oppelt PG, Hauffa BP, Dörr HG. Young women with ullrich-turner syndrome. recommendations of an expert workshop on the transition to adult medicine. Gynäkologe 2014;47(2):135-44.

Quinkler M, Beuschlein F, Hahner S, Meyer G, Schöfl C, Stalla GK. Adrenal cortical insufficiency - A life threatening illness with multiple etiologies. Deutsches Ärzteblatt International 2013;110(51-52):882-8.

Stalla GK, Athanasoulia AP, Führer D, Frank-Herrmann P, Oppelt PG, Hauffa BP, Dörr HG. Transition of young women with turner syndrome to adult medicine: Current recommendations of an expert workshop. Monatsschr Kinderheilkd 2013;161(12):1180-6.

Kopp C, Theodorou M, Poullos N, Astner ST, Geinitz H, Stalla GK, Meyer B, Molls M, Nieder C, Grosu A-. Fractionated stereotactic radiotherapy in the treatment of pituitary adenomas. Strahlenther Onkol 2013;189(11):932-7.

Auer MK, Höhne N, Bazarra-Castro MÁ, Pfister H, Fuss J, Stalla GK, Sievers C, Ising M. Psychopathological profiles in transsexuals and the challenge of their special status among the sexes. PLoS ONE 2013;8(10).

Mayr B, Buslei R, Theodoropoulou M, Stalla GK, Buchfelder M, Schofl C. Molecular and functional properties of densely and sparsely granulated GH-producing pituitary adenomas. Eur J Endocrinol 2013;169(4):391-400.

Auer MK, Fuss J, Stalla GK, Athanasoulia AP. Twenty years of endocrinologic treatment in transsexualism: Analyzing the role of chromosomal analysis and hormonal profiling in the diagnostic work-up. Fertil Steril 2013;100(4):1103-10.

Theodoropoulou M, Stalla GK. Somatostatin receptors: From signaling to clinical practice. Front Neuroendocrinol 2013;34(3):228-52.

Auer M, Stalla GK, Athanasoulia AP. Isolated gonadotropic deficiency after multiple concussions in a professional soccer player. Dtsch Med Wochenschr 2013;138(16):831-3.

Monteserin-Garcia J, Al-Massadi O, Seoane LM, Alvarez CV, Shan B, Stalla J, Paez-Pereda M, Casanueva FF, Stalla GK, Theodoropoulou M. Sirt1 inhibits the transcription factor CREB to regulate pituitary growth hormone synthesis. FASEB Journal 2013;27(4):1561-71.

Dimopoulou C, Ising M, Pfister H, Schopohl J, Stalla GK, Sievers C. Increased prevalence of anxiety-associated personality traits in patients with cushing's disease: A cross-sectional study. Neuroendocrinology 2013;97(2):139-45.

Athanasoulia AP, Ising M, Pfister H, Mantzoros CS, Stalla GK, Sievers C. Distinct dopaminergic personality patterns in patients with prolactinomas: A comparison with nonfunctioning pituitary adenoma patients and age-and gender-matched controls. Neuroendocrinology 2012;96(3):204-11.

Renner C, Hummelsheim H, Kopczak A, Steube D, Schneider HJ, Schneider M, Kreitschmann-Andermahr I, Jordan M, Uhl E, Stalla GK. The influence of gender on the injury severity, course and outcome of traumatic brain injury. Brain Injury 2012;26(11):1360-71.

Sievers C, Sämann PG, Pfister H, Dimopoulou C, Czisch M, Roemmler J, Schopohl J, Stalla GK, Zihl J. Cognitive function in acromegaly: Description and brain volumetric correlates. Pituitary 2012;15(3):350-7.

Friedrich N, Schneider HJ, Haring R, Nauck M, Völzke H, Kroemer HK, Dörr M, Klotsche J, Jung-Sievers C, Pittrow D, Lehnert H, März W, Pieper L, Wittchen H-, Wallaschofski H, Stalla GK. Improved prediction of all-cause mortality by a combination of serum total testosterone and insulin-like growth factor 1 in adult men. Steroids 2012;77(1-2):52-8.

Perez-Castro C, Renner U, Haedo MR, Stalla GK, Arzt E. Cellular and molecular specificity of pituitary gland physiology. Physiol Rev 2012;92(1):1-38.

Schneider HJ, Klotsche J, Wittchen H-, Stalla GK, Schopohl J, Kann PH, Kreitschmann-Andermahr I, Wallaschofski H. Effects of growth hormone replacement within the KIMS survey on estimated cardiovascular risk and predictors of risk reduction in patients with growth hormone deficiency. Clin Endocrinol (Oxf) 2011;75(6):825-30.

Castillo V, Theodoropoulou M, Stalla J, Gallelli MF, Cabrera-Blatter MF, Haedo MR, Labeur M, Schmid HA, Stalla GK, Arzt E. Effect of SOM230 (pasireotide) on corticotropic cells: Action in dogs with cushing's disease. Neuroendocrinology 2011;94(2):124-36.

Schneider HJ, Schneider M, Kreitschmann-Andermahr I, Tuschy U, Wallaschofski H, Fleck S, Faust M, Renner CIE, Kopczak A, Saller B, Buchfelder M, Jordan M, Stalla GK. Structured assessment of hypopituitarism after traumatic brain injury and aneurysmal subarachnoid hemorrhage in 1242 patients: The german interdisciplinary database. J Neurotrauma 2011;28(9):1693-8.

Schneider HJ, Kosilek RP, Günther M, Roemmler J, Stalla GK, Sievers C, Reincke M, Schopohl J, Würtz RP. A novel approach to the detection of acromegaly: Accuracy of diagnosis by automatic face classification. J Clin Endocrinol Metab 2011;96(7):2074-80.

Schneider HJ, Klotsche J, Silber S, Stalla GK, Wittchen H-. Measuring abdominal obesity: Effects of height on distribution of cardiometabolic risk factors risk using waist circumference and waist-to-height ratio. Diabetes Care 2011;34(1).

Sievers C, Klotsche J, Pieper L, Schneider HJ, März W, Wittchen HU, Stalla GK, Mantzoros C. Low testosterone levels predict all-cause mortality and cardiovascular events in women: A prospective cohort study in german primary care patients. European Journal of Endocrinology 2010;163(4):699-708.

Dimopoulou C, Sievers C, Wittchen HU, Pieper L, Klotsche J, Roemmler J, Schopohl J, Schneider HJ, Stalla GK. Adverse anthropometric risk profile in biochemically controlled acromegalic patients: Comparison with an age- and gender-matched primary care population. Pituitary 2010;13(3):207-14.

Theodoropoulou M, Labeur M, Paez Pereda M, Haedo M, Perone MJ, Renner U, Arzt E, Stalla GK. Novel medical therapies for pituitary tumors. Front Horm Res 2010;38:158-64.

Berg C, Petersenn S, Lahner H, Herrmann BL, Buchfelder M, Droste M, Stalla GK, Strasburger CJ, Roggenbuck U, Lehmann N, Moebus S, Jöckel K-, Möhlenkamp S, Erbel R, Saller B, Mann K. Cardiovascular risk factors in patients with uncontrolled and long-term acromegaly: Comparison with matched data from the general population and the effect of disease control. J Clin Endocrinol Metab 2010;95(8):3648-56.

Sievers C, Brübach K, Saller B, Schneider HJ, Buchfelder M, Droste M, Mann K, Strasburger CJ, Stalla GK. Change of symptoms and perceived health in acromegalic patients on pegvisomant therapy: A retrospective cohort study within the german pegvisomant observational study (GPOS). Clin Endocrinol (Oxf) 2010;73(1):89-94.


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